Benzodiazepine is a central nervous system depressant which has anxiolytic, hypnotic, anticonvulsant and muscle relaxant effects. It is usually taken orally or nasally.  Benzodiazepines are absorbed into the stomach and small intestine and then metabolized (broken down) by the liver when taken orally.  They are then metabolized in the liver with 90%-95% excreted through the urine. Only trace amounts (less than 1%) of most benzodiazepines are excreted unaltered in the urine. Benzodiazepines are metabolized to desmethyldiazepam or oxazepam. Studies have shown that overdose and extended usage may lead to coma and possibly death. The effects of benzodiazepine generally last 4–8 hours following use.
The H&R BZO Test is lateral flow, one-step immunoassay for the qualitative detection of oxazepam in human urine at the following cut-off concentrations:
BZO   300ng/mL.
This test provides only a preliminary analytical test result which should be confirmed by a more specific method. Gas chromatography/mass spectrometry (GC/MS) has been established as the preferred confirmatory method. Clinical consideration and professional judgment should be applied to any drug test result, particularly when preliminary positive results are indicated.







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